Biomaterials for bone tissue engineering

Preparation of Hybrid Biomaterials for Bone Tissue Engineering

Tissue engineering has evolved from the use of biomaterials for bone substitution that fulfill the clinical demands of biocompatibility, biodegradability, non-immunogeneity, structural strength and porosity. Porous scaffolds have been developed in many forms and materials, but few reached the need of adequate physical, biological and mechanical properties. In the present paper we report the pre...

Piezoelectric smart biomaterials for bone and cartilage tissue engineering

Tissues like bone and cartilage are remodeled dynamically for their functional requirements by signaling pathways. The signals are controlled by the cells and extracellular matrix and transmitted through an electrical and chemical synapse. Scaffold-based tissue engineering therapies largely disturb the natural signaling pathways, due to their rigidity towards signal conduction, despite their th...

Densified collagen-fibril biomaterials for bone tissue engineering

Watkins, Lauren E. M.S.B.M.E., Purdue University, May 2016. Densified Collagen-Fibril Biomaterials for Bone Tissue Engineering. Major Professor: Sherry Voytik-Harbin. Millions of craniofacial bone defects occur annually as a result of trauma, congenital defects, disease, or tooth extraction1, 2. When present in the oral cavity, these defects are associated with adverse impacts on speech, mastic...

Biomaterials for Cardiac Tissue Engineering

Cardiovascular diseases (CVD) are a leading death cause in developed countries (1 of every 3 deaths in the United States in 2008) [1]. Changes in diet and habits are causing CVD to become major mortality pathologies in developing countries too [2] (they are already responsible for a 30% of the world deaths). This group of diseases constitutes a great burden for the national health systems, cons...

Poly(lactic acid) (PLA) Nanofibers for Bone Tissue Engineering